Coleus forskohlii: Fat-Fighting and More
نویسنده
چکیده
Coleus forskohlii, is a member of the mint family (Lamiaceae). As part of a long-standing tradition in India, C. forskohlii roots have been used as a marinated food, or pickle, that is commonly eaten as part of a vegetarian meal. Upon closer investigation into the plant's pharmacological properties, it was revealed that C. forskohlii roots contain forskolin, a compound that belongs to the chemical class of diterpenes.
منابع مشابه
Effects of Coleus forskohlii on fat storage in ovariectomized rats.
The antiobesity effects of Coleus forskohlii were investigated in ovariectomized (ovx) rats. Eight-week-old female Wistar rats were assigned to four groups: a sham-operated group fed the control diet (MF, sham-m) ; an ovx-m group fed the control diet; a sham-operated group fed the control diet containing 50 g/kg of Coleus forskohlii extract (sham-c) ; and an ovx-c group fed the control diet con...
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The in vitro antifungal activity of solvent extracts of Coleus forskohlii, Coleus blumei and Coleus barbatus were compared by testing against some pathogenic fungi like Aspergillus niger, Aspergillusfumigatus, Aspergillus ruantii, Proteus vulgaris and Candida albicans. The petroleum ether extract of Coleus forskohlii and Coleus barbatus exhibited significant antifungal activity against all the ...
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Isoforskolin (ISOF) was isolated from Coleus forskohlii native to Yunnan in China. It is identified as one analog of diterpene forskolin (FSK) which comes from the Indian plant Coleus forskohlii. Researches found that the Yunnan native plant Coleus forskohlii contained rich ISOF but not FSK. ISOF was reported to activate adenylyl cyclase (AC) isoforms. The ophthalmologic and cardiovascular effe...
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Human liver cancer is the fifth most common cancer in the world. It is one of the serious health problems in most developing countries. The present investigation proved that ethanol extract of Coleus forskohlii root extract significantly suppressed the growth and induced the apoptosis in the liver cancer (HepG2) cell lines. IC50 dose was measured with Methyl thiazolyl tetrazolium (MTT) assay. 6...
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A rapid method was developed for the evaluation of forskolin in Coleus forskohlii Briq. (Lamiaceae). Forskolin was quantitated in the root and stem of dried C. forskohlii and in 17 market products by reversed-phase liquid chromatography (LC) with a photodiode array detector at 210 nm. The temperature was held constant at 30 degrees C, and the retention time of forskolin was approximately 6.8 mi...
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